AAPS Annual Meeting and Exposition

November 14-18, 2010
Morial Convention Center
New Orleans, LA, USA


IMA North America, inc.
BOOTH # 725 

Multiparticulates are becoming more and more a popular delivery technology, because of the many advantages they offer in terms of potential for controlled release profiles, dosing flexibility and combination of different actives. Additionally, multiparticulates demonstrate a more consistent in-vivo drug release than tablets. Among the different types of multiparticulates, a growing interest is placed on minitablets, as the production process is easier, less expensive, and potentially has less scale-up issues, when compared to pellet layering or extrusion and spheronization.

IMA ACTIVE Division can offer a complete range of machine for the manufacture of multiparticulates: from granulation to tableting with multi-tip tooling, from coating and/or bead layering to final encapsulation.

Discover our innovative solutions at AAPS 2010!

The ROTO LAB is a compact benchtop High Shear Mixer Granulator and Single-Pot Processor for R&D purposes. It is used to process very small batch sizes (200 g -1000 g) carrying out the entire process, from granulation to the drying of granules, in one contained bowl. This means that contact between product, operator and environment is minimized. The ROTO LAB is suitable for the development of potent products and allows total batch reproducibility, ensuring high product yields. The tilting system of the bowl ensures gentle handling of granules during vacuum drying to prevent them breaking. The gas stripping system (GA.ST.), by injecting an inert gas through the product mass, enhances the evaporation rate. The machine guarantees a reliable monitoring of granulation and drying, an accurate detection of the process end-point and very easy cleaning operations.

The GHIBLI 003 is a modular fluid bed dryer for R&D and small batch production. Three product containers can be fitted on the same machine: Top Spray, Bottom Spray and Tangential Spray. Air flow is managed without flaps while a patented hydraulic system allows to rotate and lower machine expansion chamber. The machine is fitted with metallic filters with an innovative patented cleaning system, for filters unclogging during production and filters washing after process.

The KILIAN PRESSIMA is a rotary tablet press for galenic and research applications. It is the only press of its type equipped with an interchangeable die table, including mixed B and D toolings and different product hoppers from 5 litres to 15 litres. Force feed fill-shoe and Gravity Feed fill-shoe are also available. This very flexible machine is designed for compressing small batch production and the instrumented version allows complete control of all production parameters, including the possibility to measure the compression forces, the ejection force, upper and lower punch displacement. Good accessibility facilitates cleaning and maintenance. The machine can reach a speed up to 79,800 tablets/hour.


IMA ACTIVE Division offers a complete range of machines for the process and production of solid dose products. Granulation equipment, manufactured both by IMA and ZANCHETTA, for wet granulation and drying for all types of production and layout requirements. Tablet press machines manufactured both by IMA and by KILIAN suitable for pharmaceutical, chemical, food and cosmetic industries. Capsule filling machines with a wide assortment of filling and control systems. Coating systems with solid wall and perforated pans. Checkweighers for 100% control of tablets and capsules. Very flexible powder handling and washing systems manufactured by ZANCHETTA.

IMA LIFE offers machines for the washing and sterilising of pharmaceutical vials, filling and stoppering in aseptic environments of vials, ampoules and syringes, filling and closing of pharmaceuticals and cosmetics, microdosing of aseptic powders as well as industrial, pilot and laboratory freeze-dryers, which can be combined with the industry's widest range of automated loading and unloading system solutions. IMA LIFE also offers labellers, blowing machines, depackers and traying machines.

IMA SAFE is the only manufacturer to offer complete primary and secondary packaging line solutions to the pharmaceutical, toiletry, cosmetic and food industries. Blister machines have speed ranges from low to super high speed (1,300 blisters/minute). Low speed machines are also manufactured by the subsidiary IMA-PG India. Tablet counting machine production includes IMA SAFE NOVA (USA) and IMA SAFE SWIFTPACK (UK). Tube fillers are manufactured by IMA SAFE CO.MA.DI.S., while horizontal and vertical cartoners are manufactured by IMA SAFE. IMA SAFE LINE offers a complete range of end-of-line equipment which includes over-wrapping, shrink-wrapping, case packing and palletizing solutions. A new collaboration is also in place with UNIVERSAL PACK, one of the major experts in the field of stick-packing, shaped and heat-sealed on four sides.


For more info : exhibitions@ima.it